Seasonal changes in adrenoreactivity and a modification in the fractional phospholipid composition of the frog bladder

: The study has shown seasonal changes in the responses of the frog bladder isolated preparation to exogenous adrenalin. The finding is explained by heterogeneity of the smooth muscle adrenoreceptors and alteration of functionally domineering populations during the winter-spring cycle. The changes corresponded to modifications of the fraction composition of phospholipids, the modifications being, probably, one of the ways of regulation of the smooth muscle adrenoreceptor apparatus' activity.