Treatment of Ewing's Sarcoma

Ewing's sarcoma has been traditionally known as a malignant bone tumor associated with a very poor prognosis. We have treated eight patients with diagnosis of Ewing's sarcoma from 1968 to 1988. Five of these were females and others males. Primary bony lesions of five patients were four trunks and one proximal extremity. Three were distal extremities. Before 1975, four patients were treated with surgery, radiation and one or two drugs' administration. In result, three of these died within two years. One's prognosis was uncertan. Since 1977, three of four patients were treated with Rosen's adjuvant chemotherapy, but one (female) was not treated because she refused this treatment. Consequently, three of four patients died within three years. Now, one (female) has been treated with Rosen's adjuvant chemotherapy (Tll) and radical operation. She has been alive without metastasis and recurrence of the tumor during eleven months. It has been reported that the therapeutic result of Rosen's adjuvant chemotherapy is good. And then our patients have been treated with the adjuvant chemotherapy.