Synthesis of novel thiazole, pyranothiazole, thiazolo[4,5- b ]pyridines and thiazolo[5′,4′:5,6]pyrano[2,3- d ]pyrimidine derivatives and incorporating isoindoline-1,3-dione group

Mona Hosny,Yasser H. Zaki,Wafaa A. Mokbel,Abdou O. Abdelhamid

Synthesis of novel thiazole, pyranothiazole, thiazolo[4,5- b ]pyridines and thiazolo[5′,4′:5,6]pyrano[2,3- d ]pyrimidine derivatives and incorporating isoindoline-1,3-dione group

2019

Mona Hosny
Yasser H. Zaki
Wafaa A. Mokbel
Abdou O. Abdelhamid

Background Thiazole is a core structural motif presents in a wide range of natural products. Thiazole derivatives also have a wide range of medicinal and biological properties.

Keywords:

Stereochemistry
Pyrimidine
Structural motif
Thiazole
Isoindoline
Chemistry
Triethylamine
antitumor activity
Medicinal chemistry
biological property
Pyridine
Ethanol

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