Anticardiolipin antibodies in children with portal vein thrombosis

Summary Aim: The aim of this study was to evaluate the frequency of anticardiolipin antibodies in children with portal vein thrombosis and whether anticardiolipin antibodies have effect on thrombosis in the portal vein. Material and Method: IgG and IgM anticardiolipin levels were measured in 20 patients with portal vein thrombosis and in 20 healthy controls using an ELISA method. Results: IgG anticardiolipin levels (GPL unit) were found as 13.9±4.8 in the portal vein thrombosis patients and 4.4±1.9 in the control group (p 0.05). In seven (35%) portal vein thrombosis patients and in one (5%) in the control group anticardiolipin IgG (p 0.05) levels were high (>10 GPL and MPL unit). Conclusions: IgG anticardiolipin antibodies are significantly associated with portal vein thrombosis in children. (Turk Arch Ped 2009; 44: 124-6)