BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module
2007
Apoptotic cells must be removed by phagocytes to avoid local inflammation. They expose phosphatidylserine, which is normally restricted to the inner leaflet of the plasma membrane, on their surface, acting as an 'eat-me' signal. This paper shows that the BAI1 protein is an upstream receptor for phosphatidylserine in mammalian macrophages
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