Renal impairment and outcome in patients with takotsubo cardiomyopathy

Abstract Objectives The objectives were to ascertain the prevalence of renal impairment among patients with a takotsubo cardiomyopathy (TTC) episode and whether clinical outcomes are related to renal function. Methods A total of 108 consecutive subjects with TTC were enrolled in a multicenter registry and followed for a mean period of 429days. Renal function was evaluated during hospitalization in terms of acute kidney injury/failure and estimated glomerular filtration rate (eGFR). Incidence of death, rehospitalization, and recurrence of TTC during follow-up was recorded. Results Raised creatinine levels can be found during hospitalizations for TTC episodes (analysis of variance P r = −0.28, P P 2 ]) vs those with eGFR >60mL/(min 1.73m 2 ) was 1.817 (95% confidence interval, 1.097-3.009; P Conclusions Raised creatinine levels and impaired renal function may be found in patients with TTC. Lower eGFR values during hospitalization are associated with longer hospitalizations and higher rates of adverse events at follow-up. Renal function during a TTC episode should be carefully evaluated.