NON HODGKIN'S LYMPHOMA — A STUDY

The objective of the study was to determine the frequency and pattern of Non Hodgkin’s lymphoma (NHL) in adults in a tertiary care hospital. This retrospective study was conducted at Histopathology Department, Dr. Ziauddin Hospital over a period of 09 years, from 2003 to 2011. 192 cases of Non Hodgkin’s lymphoma (NHL) were retrieved from surgical pathology record. After routine H & E stain examination, a panel of immunohistochemical stains was applied on formalin fixed paraffin embedded tissue. The data was analyzed for type of lymphoma, age & sex distribution, site of biopsy and immunophenotypic features. Out of 192 cases of Non Hodgkin’s lymphoma (NHL), 132 (69%) were males & 60 (31%) were females. Mean age of patients was 46.7 years and median age was 47 years. B cell lymphoma was out numbered (87%) than T cell lymphoma (13%). Diffuse large B-Cell lymphoma was the commonest (113) B cell lymphoma followed by other types of lymphoma. 52% cases were from extra nodal sites followed by 34% of nodal lymphoma. Site of biopsy was not mentioned in 14% cases. In adults, B cell Lymphoma is more frequent than T cell Lymphoma with Diffuse large B-cell