Determination of antimicrobial activity of different extracts of Enteromorpha intestinalis (Linnaeus Nees.1820) against pathogenic microorganisms

It is known that components such as polyphenols, flavonoids and polysaccharides have antimicrobial activity in macroalgae in aquatic environments. In this study, it was aimed to determine the antimicrobial activities of E.intestinalis (L.) Nees methanol, 70% ethanol and water extracts against different pathogenic microorganisms, which are economically important marine macroalgae. According to Broth Microdilution Method; Antimicrobial activities of different extracts of the studied species against Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Staphylococcus aureus, Salmonella enteritidis, Sarcina lutea and Bacillus cereus standard bacterial strains and Candida albicans fungus strain were evaluated by determining the Minimum Inhibition Concentration (MIC).According to the findings, it was observed that the water extract of the studied species showed no antimicrobial activity against any test organism. The methanol extract of E.intestinalis was found to have antimicrobial activity against Pseudomonas aeruginosa, Staphylococcus aureus, Sarcina lutea ,Bacillus cereus and Candida albicans strain, while ethanol extract was observed against Pseudomonas aeruginosa ,Sarcina lutea and Candida albicans strains. The highest antibacterial effect was observed in E.intestinalis (L.) Nees methanol extract and the most effective strain was Bacillus cereus (0.390 mg/ml). Nowadays, algae are of great importance in terms of being very useful drug raw material, containing the basic components, being more effective and less toxic, as well as being models for drugs with original drug-like physiological activity. Since the data obtained with this study are intended for prospective application, it is thought that alternative drug applications will be provided as a basis for the studies aimed at reducing the use of commonly used antibiotic and antifungal agents against pathogenic microorganisms.