Oligopeptides with inhibitory activity of renin, their preparation and use.

Compounds of formula (I), (wherein A is a bond -CO C A I C 1 TO 3; B is a group or an alkylene IMINO alkylene 1 O 2 C R1 is a ALQULILO or alkoxy of 1 A 4 C, A GROUP ETEROCICLICO or amino optionally SUSTRITUIDO; R2 is a phenyl or naphthyl optionally substituted; R3 is TIOZOLILO, isoxazolyl or imidazolyl; R4 is isopropyl or CILCOEXILO; R5 and R6 are alkyl of 1 to 4 CO BY THE aTOM C to which they are attached form a cycloalkyl of 3 to 7 C; R7 is H or alkyl of 1 to 6 C optionally substituted and R8 is H or alkyl of 1 to 4 C), HAS Inhibitory Activity renin and therefore hypotensive and are valuable IN THE DIAGNOSIS AND TREATMENT OF HYPERTENSION INDUCED ALTERATIONS IN THE SYSTEM Renin ANGIOTENSINA.SE be prepared by reacting the appropriate amino acids, oligopeptides or derivatives INFERIORES