Effectiveness of Leukocyte Immunotherapy in Recurrent Spontaneous Abortion

Objectives:To evaluate the effectiveness of leukocyte immunization therapy for treatment of recurrent spontaneous abortion (RSA).Methods:454 non-pregnant women recognized as RSA were referred for immunotherapy,all the cases were immunized by isolated lymphocytes from their husbands.Patients up to 20 weeks in gestation were recognized as successfully treatment outcome.116(25.55%)cases out of 454 were given birth,the totally efective rate was 70.48%(not including gestation before 20th week),we found 1 fetal suffered with anencephaly and 1 congenital heart disease,the malformation rate was 0.44%.Conclusion:The results showed evidence that immunotherapy is one of the effective and safe methods for RSA.