Additional file 1: Figure S1. of Boiogito, a Kampo medicine, improves hydrarthrosis in a rat model of knee osteoarthritis

Histochemical changes in joints of rats with osteoarthritis. Cartilage surface irregularities, diffuse hypercellularity, and decreased Safranin O staining were seen in joints of rats with OA 4 weeks after surgery. Daily administration of boiogito and indomethacin partially tended to alleviate the histochemical changes in articular cartilage of rats with OA. (PDF 250 kb)