Tobacco Treatment Outcomes in Patients With and Without a History of Depression, Czech Republic, 2005-2010
2013
Introduction Higher prevalence of smoking among depressed
patients, as well as the risk of depression in smokers, is well
documented. The proportion of patients with a history of
depression among those seeking intensive treatment of tobacco
dependence is also high. In contrast, evidence of treatment
success in this subgroup of patients is controversial. The aim
of this study was to compare smoking abstinence rates after
tobacco treatment in smokers with and without a history of
depression. Methods We reviewed retrospective data from 1,730
smokers seeking treatment in Prague, Czech Republic. History of
depression was defined as past diagnosis of depression or
current treatment of depression. After a 1-year, self-reported
smoking status was validated by expired-air carbon monoxide. We
used logistic regression to analyze associations between
abstinence rates, history of depression, and other factors (eg,
age, sex, tobacco dependence). Results Of 1,730 smokers
treated, 289 (16.7%) had a history of depression. The smoking
abstinence rate at 1 year was 32.5% for smokers with a history
of depression and 38.7% for those with no history (P = .048).
Among women, abstinence did not differ between groups (35.0% vs
35.7%; P = .86). However, among men, those with a history of
depression had lower rates of abstinence (27.4% vs 41.3%; P =
.009). After adjustment for baseline covariates, history of
depression was not significantly associated with smoking
abstinence in men or women. Conclusion Intensive outpatient
tobacco treatment programs can achieve abstinence rates among
smokers with a history of depression similar to rates among the
general population.
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