OUTCOME OF THROMBOLYTIC AND NONTHROMBOLYTIC THERAPY IN ACUTE MYOCARDIAL INFARCTION

OBJECTIVE: To compare morbidity, in hospital mortality and benefits of Streptokinase (SK) therapy and Non- Streptokinase (non-SK) therapy in acute myocardial infarction patients. METHODS: Retrospective review of the medical record of 300 patients with all types of acute MI admitted in our CCU between Nov. 2000-April 2001. RESUTLS: Out of 300 patients, 210 (70%) were male and 90 (30%) were female. 150 (50%) were given SK therapy and 150 (50%) did not receive SK therapy because they did not qualify. Mean age was 55 years. The success of SK therapy was judged indirectly through non-invasive measures. LIMITATIONS: This data is from a hospital which does not have invasive or PCI facilities, hence it was totally dependant on non-invasive measures. However, this might help in patient management in our society where most hospitals/CCUs do not have invasive facilities. CONCLUSION: The overall survey shows that not only mortality was improved in SK group but also patients had less complications, early pain relief and shorter hospital stay. However, due to higher earlier event rate in SK group, these patients should preferably be referred to a facility having interventional support.