Regioselective Intramolecular Aldol Condensation by Using Excess Morpholine-Camphoric Acid

Regioselective intramolecular aldol condensations of type I dialdehydes were explored under various reaction conditions, including those of the Woodward and the Corey methods. The results obtained by the use of excess morpholine-camphoric acid are given in Table I in comparison with those obtained by the previous methods. The structure assignments of products by nuclear magnetic resonance analysis are also described.