Method Development : Quantitative Determination of Polysorbate 80 in Gammanorm® and Poloxamer 188 in Octagenate® Using Hydrophilic Interaction Liquid Chromatography Coupled with Evaporative Light Scattering Detection

Per Aronsson

Method Development : Quantitative Determination of Polysorbate 80 in Gammanorm® and Poloxamer 188 in Octagenate® Using Hydrophilic Interaction Liquid Chromatography Coupled with Evaporative Light Scattering Detection

2012

Per Aronsson

Polysorbate 80 (PS80) and Poloxamer 188 (P188) are non-ionic detergents used as surfactants in the injection fluids Gammanorm® (human immunoglobulin) and Octagenate® (recombinant human factor VIII) ...

Keywords:

Poloxamer
Polysorbate 80
Hydrophilic interaction chromatography
Recombinant human factor VIII
Materials science
Light scattering
Chromatography
quantitative determination
human immunoglobulin
method development

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