Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets.

Lambert Yue,Michael McPhee,Kevin Gonzalez,Mark Charman,Jonghwa Lee,Jordan Thompson,Dirk F.H. Winkler,Rosemary B. Cornell,Steven L. Pelech,Neale D. Ridgway

Differential dephosphorylation of CTP:phosphocholine cytidylyltransferase upon translocation to nuclear membranes and lipid droplets.

2020

Lambert Yue
Michael McPhee
Kevin Gonzalez
Mark Charman
Jonghwa Lee
Jordan Thompson
Dirk F.H. Winkler
Rosemary B. Cornell
Steven L. Pelech
Neale D. Ridgway

CTP:phosphocholine cytidylyltransferase (CCT) α and CCTβ catalyze the rate-limiting step in phosphatidylcholine (PC) biosynthesis. CCTα is activated by association of its α-helical M-domain with nu...

Keywords:

Chromosomal translocation
Cytidylyltransferase
Cell biology
Biology
Membrane
Phosphocholine
Dephosphorylation
Phosphatidylcholine
Biosynthesis
Lipid droplet
Enzyme
CTP Phosphocholine Cytidylyltransferase
Biophysics
Phosphatidylcholine synthesis

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