Inflammatory Choroidal Vascular Membranes

Inflammatory choroidal neovascularization (CNV) is a sight threatening complication of noninfectious and infectious uveitic disorders. It is the third most common cause of CNV after age-related macular degeneration (AMD) and pathologic myopia. In this review, we provide an overview of inflammatory CNV including a review of the pathogenesis, the spectrum of clinical presentations, the various multimodal retinal imaging findings, and the management guidelines. We also describe the diagnostic challenge of differentiating inflammatory lesions from secondary CNV, providing some guiding principles in making this distinction. Lastly, we discuss the essential aspects of therapeutic management, emphasizing the importance of targeting both the inflammatory and neovascular disease components.