An Obscure Cause of Leg Edema, Non-Hodgkin's Lymphoma

United States, with an incidence of approximately 60,000 cases per year. About 85% of patients with malignant lymphoma have non-Hodgkin’s lymphoma, low grade or high grade. The incidence of NonHodgkin’s Lymphoma (NHL) is increasing, particularly, among elderly and patients with AIDS. 1 In recent years, incidence of NHL is also found to be increasing in Pakistan. 2 Diffuse B-cell lymphoma is the most common non-Hodgkin’s lymphoma.3 Mean age of presentation is 60 years with slight male predominance. Diffuse large cell lymphoma usually presents with rapidly enlarging symptomatic mass at a single nodal or extra-nodal site, B-symptoms, involvement of GIT, skin, bone or brain.4 Here, we report a case of 25 years old female, who had NHL. She presented with exclusively gross and progressively increasing edema of unilateral lower limb without generalized lymphadenopathy, B-symptoms, skin rash or other relatively pertinent symptoms. Diagnosis of NHL in this case was incidental when enlarged lymph nodes were found during surgical decompression of initially suspected psoas abscess, which, on histopathological examination, revealed malignant NHL (diffuse large cell type). Age of presentation and mode of presentation (mimicking psoas abscess), in the absence of lymphadeno-pathy, are both rare for NHL.5,6