Synthesis and Antifungal Evaluation of Quaternary Ammonium Salts Derivatives of Dialkylaminoethyl Methacrylate Bearing 1,3,4-Oxadiazoles Moieties

Starting from lauric acid two novel quaternary ammonium salts containing 1,3,4- Oxadiazoles nucleus derivative from N,N-Diethylaminoethyl Methacrylate (DEAEMA) and N,N- Dimethylaminoethyl Methacrylate (DMAEMA) was successfully synthesized and characterized by IR, 1 H and 13 C NMR, All the synthesized compounds were evaluated for their preliminary in vitro antifungal activity against three fungal strains such as Fusarium oxysporum , Fusarium commune and Fusarium rodelens. The synthesized compounds showed promising antifungal potential against the phytopathogenic test fungi.