Lower expression of tight junction protein 1 gene and increased FOXP3 expression in the small bowel mucosa in coeliac disease and associated type 1 diabetes mellitus.

Tamara Vorobjova,Oivi Uibo,Ivi Ojakivi,Kaupo Teesalu,Marina Panarina,Kaire Heilman,Raivo Uibo

Lower expression of tight junction protein 1 gene and increased FOXP3 expression in the small bowel mucosa in coeliac disease and associated type 1 diabetes mellitus.

2011

Tamara Vorobjova
Oivi Uibo
Ivi Ojakivi
Kaupo Teesalu
Marina Panarina
Kaire Heilman
Raivo Uibo

Background: The role of regulatory T cells expressing FOXP3 in the pathogenesis of coeliac disease (CD) and type 1 diabetes (T1D) has been reported. Recent data have placed special

Keywords:

Immunology
Type 1 diabetes
Pathogenesis
Regulatory T cell
FOXP3
Coeliac disease
Tight junction protein 1
Immune tolerance
Endocrinology
Biology
Internal medicine
Diabetes mellitus
intestinal mucosa
Small intestine
Tissue transglutaminase
Immunoglobulin A

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