ОСОБЛИВОСТІ ПЕРЕБІГУ ГОСТРИХ КИШКОВИХ ІНФЕКЦІЙ, СПРИЧИНЕНИХ УМОВНО-ПАТОГЕННИМИ МІКРООРГАНІЗМАМИ ТА ВІРУСАМИ, В СУЧАСНИХ УМОВАХ

SUMMARY. It is proved that in the etiological structure of acute intestinal infections Klebsiella pneumoniae (31,4 %), viruses (15,7 %), EPKP (11,4 %), Pseudomonas aeruginosae (10,0 %) (p <0.01) predominate in the modern context. Performed exploration of integrated intoxication markers of the first level (body temperature, nausea, vomiting, weakness, headache, abdominal pain any location, etc.) allowed to state that in acuity endogenous intoxication increases in all patients (p <0,05-0,001). Integrative indicators of endogenous intoxication significantly elevated in all patients point at pronounced intoxication syndrome in the acute period. There is an increase of leukocyte index of intoxication ( 4,3-5,5 times), hematological toxicity index ( 5,0-7,4 ), the index of leukocytes shift ( 2,1-2,6 ). Instead lymphocytic index decreases significantly (2,0-2,2 times). While investigating the microbiocenosis of intestinal canal in the acute period is was found the decrease of the bifid bacterium, lactobacilli and Escherichia coli number with increasing levels of other UPM representatives, hemolytic E. coli and genus Candida fungi (p <0,05-0,001). Key words: acute intestinal infection, clinical findings, epidemiology, integrative indicators of endogenous intoxication, microbiocenosis of intestinal canal.