Methods and devices to produce a lasting change in neural function of a patient.

Device for effectuating a neural-function of a patient associated with a first location of the brain of patient comprising occur: a diagnostic system capable of identifying a stimulation site in the cortex of the patient by determining a region of the brain in which it is present a neural activity planned in response to generating the intended neural activity remotely from the first location of the brain; and a stimulation system that comprises a flexible or compressible support, an electrode on the support member configured to be implanted at the stimulation site between the skull and the surface of the pia mater of the brain and a pulse generator to provide a electrical potential to the electrode.