Two cases of Kabuki make-up syndrome with cleft palate

The authors wish to report on two clinical cases of Kabuki make-up syndrome, together with some bibliographical comments.The clinical features of these cases were characterized by maldevelopment, stunted skeletal development, peculiar face, fingertip pads and cleft palate.Case No.2 was infected with cytomegalo-virus two months after birth. At the same time his mother also showed positive reaction of IgM antibody of cytomegalo-virus. Therefore, it was doubtful that congenital infection by cytomegalo-virus are present in case No.2.It is assumed that the infection of cytomegalo-virus exerted any influence on the possibility of cause of Kabuki make-up syndrome in case 2.