Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with N-toluenesulfonyl aldimines

Kazumi Okuro,Howard Alper

Palladium-catalyzed intermolecular cyclocarbonylation of 2-iodoanilines with N-toluenesulfonyl aldimines

2012

Kazumi Okuro
Howard Alper

Abstract A single step synthesis of 2,3-dihydro-4(1 H )-quinazolinones is described using palladium-catalyzed cyclocarbonylation of 2-iodoanilines with N -toluenesulfonyl aldimines.

Keywords:

Aldimine
Medicinal chemistry
Quinazolinone
Palladium
Catalysis
Chemistry
Intermolecular force
Organic chemistry
single step

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