The Clinical Study of the Risk Factors of Type 2 Diabetes Mellitus with Vascular Lesions of Lower Extremities

2011 
Objective To explore the risk factors of the Type 2 Diabetes Mellitus(T2DM) patients with vascular lesions of lower extremities.Methods All 86 T2DM patients who had suffered vascular lesions of lower extremities were divided into the observed group,86 patients who had not suffered vascular lesions of lower extremities were divided into the compared group.We detected the following parameters:cholesterol,glycerin trilaurate,high density lipoprotein,blood uric acid,fasting blood-glucose,body mass index,course of disease,blood pressure and the C reaction protein(CRP).Compared the difference of these parameters of both groups.Correlation analysis and logistic regression analysis were used to explore the risk factors of the T2DM patients with vascular lesions of lower extremities.Results The rate of hypertension,systolic pressure,fasting blood-glucose,the course of disease,blood uric acid and CRP were significantly higher in the observed group than those in the compared group.The course of disease,systolic pressure,blood uric acid and CRP positively correlate with vascular lesions of lower extremities in observed group according to both correlation analysis and logistic regression analysis.Conclusion The course of disease,systolic pressure,blood uric acid and CRP are independent risk factors of vascular lesions of lower extremities in patients of T2DM,and getting too much food with purine did not increase the rate of vascular lesions of lower extremities.
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