Parametrization histological grade white adipose tissue of the breast by the cubic spline interpolation

ABSTRACT The noninvasive optical techniques have attracted considerable interest in recen t years, because these techniques provide lot of information on the structure and composition of biological tissues more quickly and painlessly, in this study classifies the degrees of histological differentiation of neoplastic tissue of the breast in white adipose tissue samples through numerical pametrizacion of the diffuse reflection spectra using the Fourier series approximation. The white adipose tissue is irradiated with the sp ectrophotometer MiniScan XEplus and it fr om a mastectomy of patients with aged 38 and 50 who have a cancer lesion in the breast. The samples were provided by the pathologist with theirs medical report, it which we indicate the histological grade of tumor. We performed a parameterization algorithm where the classification criterion is the modulus of the minimum difference between the numerical approximation coefficients = U and average numerical approximation coefficients obtained for each histological grade =