Mitochondrial DNA instability in malignant melanoma of the skin is mostly restricted to nodular and metastatic stages.
2004
Ultraviolet (UV) radiation is thought to be a major contributor to the development of sporadic malignant melanoma of the skin. It may induce alterations in genomic or mitochondrial DNA (mtDNA), especially C to T or CC to TT changes. Mutations or other alterations in mtDNA have been reported in a var
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