The effect of mannose binding lectin gene polymorphisms on susceptibility to tuberculosis in different ethnic groups

In order to investigate the role of MBL gene polymorphisms in susceptibility to tuberculosis (TB) we genotyped 487 TB cases and 232 controls. Among African-American individuals, the frequency of B allele was lower among controls than cases (p<0.01), but we found no differences between cases and controls of white and Hispanic ethnicity.