Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy

Aims/hypothesis Emerging evidence suggests that statins exert beneficial effects beyond those predicted by their cholesterol-lowering actions. We investigated whether atorvastatin influences the development of left ventricular (LV) dysfunction, independently of cholesterol-lowering, in an experimental model of type 1 diabetes mellitus cardiomyopathy.