Developmentally Regulated Glial and Neuronal Antigens Detected by Monoclonal Antibodies

Cell interactions must play an essential role in the implementation of the genetic programme. Cell signals during ontogenesis could modulate and, in some cases, determine choices in the processes of cell multiplication, differentiation, maturation, migration, and establishment of connections. This implies that, at molecular levels, the expression of each genetically coded signal molecule, giver (effector) and receiver (receptor), is also modulated by the preceding and the following cell interaction. Thus, in many cases the presence of signal effectors and/or receptors in a given cell should be necessary only for the required time.