Penicillamine-induced pemphigus erythematosus

: Pemphigus erythematosus occured in a patient with rheumatoid arthritis who was treated with D-penicilla-mine. The skin lesions appeared 4 months after the onset of D-penicillamine treatment and persisted 14 years after cessation of this drug. Topical betamethasone dipropionate applications resulted in complete regression of the cutaneous lesions.