Guidelines for the prescription of allergen immunotherapy and patient follow-up — Clinical questions and revision of the literature

Allergen immunotherapy (AIT) for respiratory allergens is the only curative treatment for allergies We previously published the list of the French National Clinical Practice Guidelines for AIT prescription and patient's monitoring To carry out this work, a group of more than 50 French allergists wrote an exhaustive text answering 50 clinical questions that meet the specific needs of AIT prescribers These questions have been classified into 7 groups, to focus on patient's choice, the indications and modalities of AIT prescription, treatment regimens, the routes of administration of AIT, its efficacy and safety, the choice of the allergen, patients’ follow-up and on other practical aspects that allergists may wonder about when prescribing such treatment Answers to the 50 questions are based on the results of studies published in the literature, and, if hard data could not be found, on experts’ advice The main goal of this work is to provide prescribers a clear picture of the most recent data and to guide them in choosing the optimal treatment for their allergic patients, taking into account the practical questions, which also include a look to the current clinical context, due to the SARS-CoV-2 pandemic © 2020 Elsevier Masson SAS