Effects of diadenosine tetraphosphate on systemic and regional hemodynamics in dogs

Purpose. Diadenosine tetraphosphate (AP4A) produces vasodilation and hypotension. If AP4A is to be employed clinically, its influence on systemic and regional hemodynamics needs to be investigated. In this study, we observed systemic and regional hemodynamics during reduction of mean arterial pressure (MAP) induced by AP4A in dogs.