Development of a Level A in Vitro-in Vivo Correlation for Veliparib (ABT-888) Extended Release Tablet Formulation

Rajendar K. Mittapalli,Silpa Nuthalapati,Alyssa E. Delke DeBord,Hao Xiong

Development of a Level A in Vitro-in Vivo Correlation for Veliparib (ABT-888) Extended Release Tablet Formulation

2017

Rajendar K. Mittapalli
Silpa Nuthalapati
Alyssa E. Delke DeBord
Hao Xiong

Purpose The aim of the current manuscript is to develop and validate a level A in vitro-in vivo correlation (IVIVC) for veliparib extended-release (ER) tablet formulations.

Keywords:

Veliparib
IVIVC
Pharmacology
In vivo
Chemistry
Pharmacokinetics
Correlation
Chromatography
extended release
Dissolution testing
Cmax
Bioavailability

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