One Mesh to Rule Them All: Registration-Based Personalized Cardiac Flow Simulations

The simulation of cardiac blood flow using patient-specific geometries can help for the diagnosis and treatment of cardiac diseases. Current patient-specific cardiac flow simulations requires a significant amount of human expertise and time to pre-process image data and obtain a case ready for simulations. A new procedure is proposed to alleviate this pre-processing by registering a unique generic mesh on patient-specific cardiac segmentations and transferring appropriately the spatiotemporal dynamics of the ventricle. The method is applied on real patient data acquired from 3D ultrasound imaging. Both a healthy and a pathological conditions are simulated. The resulting simulations exhibited physiological flow behavior in cardiac cavities. The experiments confirm a significant reduction in pre-processing work.