Effects of right stellate ganglion block on the function of autonomic nervous system in patients with type 2 diabetes mellitus

Objective To evaluate the effects of right stellate ganglion block on the function of autonomic nervous system in the patients with type 2 diabetes mellitus.Methods Right stellate ganglion block was performed in fifty patients with type 2 diabetes mellitus.Mean arterial pressure(MAP),heart rate(HR) and heart rate variation [(low frequency(LF),high frequency(HF),LF/HF ratio] were recorded and compared before and after right stellate ganglion block.Results Compared to before,HR was reduced[(84.6±6.5) beating/min vs.(72.3±4.4) beating/min](P0.05),but MAP was not significantly changed after right stellate ganglion block.LF and LF/HF were significantly lower after right stellate ganglion block than those before [(110.2±17.5) vs.(76.1±18.4) and(2.42±1.41) vs.(1.52±1.32),respectively].Conclusion Right stellate ganglion block can improve the balance of autonomic nervous system by regulating sympathetic-vagus nerve activity in diabetic patients with cardiovascular autonomic neuropathy.