Cooperative Signaling between Oncostatin M, Hepatocyte Growth Factor and Transforming Growth Factor-β Enhances Epithelial to Mesenchymal Transition in Lung and Pancreatic Tumor Models

Gretchen M. Argast,Peter Mercado,Iain J. Mulford,Matthew O’Connor,David M. Keane,Salam Shaaban,David M. Epstein,Jonathan A. Pachter,Julie L.C. Kan

Cooperative Signaling between Oncostatin M, Hepatocyte Growth Factor and Transforming Growth Factor-β Enhances Epithelial to Mesenchymal Transition in Lung and Pancreatic Tumor Models

2011

Gretchen M. Argast
Peter Mercado
Iain J. Mulford
Matthew O’Connor
David M. Keane
Salam Shaaban
David M. Epstein
Jonathan A. Pachter
Julie L.C. Kan

Epithelial to mesenchymal transition (EMT) plays a dual role in tumor progression. It enhances metastasis of tumor cells by increasing invasive capacity and promoting survival, and it decreases tumor

Keywords:

Oncostatin M
Epithelial–mesenchymal transition
Growth factor
Metastasis
Tumor progression
Hepatocyte growth factor
Pancreatic tumor
Cancer research
Transforming growth factor
Biology
Cancer

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations