EMLA cream in the treatment of post-herpetic neuralgia. Efficacy and pharmacokinetic profile.

Abstract The analgesic efficacy of 5% EMLA cream (5 or 10 g) when applied for 24 h periods was evaluated in 5 female and 7 male patients (mean age 69 years, range 50–85 years) with refractory post-herpetic neuralgia (PHN). Mean visual analogue pain intensity scores for all patients were significantly improved 6 h after application ( P P P P