820 Late Preterm Deliveries and Neonatal Outcomes in Multicentre French Regional Perinatal Network

Objective The objective of the study was to present the neonatal outcomes for late preterm birth by gestational age at 33.34 and 35 weeks in a multicentric neonatal network. Study Design This was a retrospective analysis of neonatal outcomes of late preterm infants (33, 34 and 35 weeks groups) in 5 neonatal care units with one University Hospital Level 3 NICU in one regional perinatal network during 2010. Data were analyzed using Chi(2), Stuent’s Test, and one way ANOVA test. Results During 2010, the rate of late preterm birth 299/8718 births: 3.42±0.94% without significant difference between the 5 centres. Rates were 0.62%, 1.35% and 1.46% respectively at 33, 34 and 35 wks. There was 19% of twin pregnancy. Vaginal birth rate (57.6%) was not significantly different between groups. Increased gestational age was associated with decreased antenatal steroid use (80.8%, 47.4% and 20.6% respectively; p=0.001). Neonatal mortality was 2/299 (0.68%). Postnatal transport was low (4.3% at 33, 4.1 at 34 and 5.6 at 35). Respiratory distress decreased (27.8% at 33 vs 8.5% at 34 and 7.9% at 35; p=0.001) without significant difference in the use of surfactant. Feeding problems decreased (20.4% at 33 vs 5.5% at 35; p=0.01). There was no significant difference in gestational age at hospital discharge between groups (37.07±1.3 at 33, 36.9±1.2 at 34 and 37.3±1.1). Conclusion Compared to recent studies the rate of late preterm delivery in our region was similar. Low rate of postnatal transport showed good organization of the regional perinatal network.