Oncologists perceptions and behaviors regarding genomic-based targeted therapy: Findings of a pilot study.

e17560 Background: Little is known about oncologists’ knowledge, perception, and utilization of genomic-based targeted therapy (GBTT) in routine practice. The objective of this pilot study was to elicit oncologists’ beliefs and practices surrounding genomic medicine in lung cancer management. Methods: We conducted individual interviews with 10 oncology fellows to elicit perceptions of GBTT in four domains: 1) knowledge; 2) attitudes; 3) intent; and 4) barriers and facilitators for practicing genomic-based targeted therapy in an academically affiliated VA medical center. Results: Analysis of the pilot interviews reflected varying degrees of knowledge regarding genomic testing and therapy. Although the majority of participants reported they referred to the guidelines when making testing and treatment decisions, some gaps in knowledge were reported, such as the use of GBTT in 2nd and 3rd line settings. Participants’ attitudes toward GBTT and support for testing and treatment were consistently positive. The m...