Impact on therapeutic index of a chronomodulated infusion at conventional doses of oxaliplatin (OHP), 5-fluorouracil (5-FU) and folinic acid (AF) in not previously treated metastatic colorectal cancer patients: A multicentric observational study

M. Pirovano,A. Zambelli,F. Gherardi,S. Masseroni,A. Nasisi,L. Paraboni,G. Martignoni,M Meregalli,C. S. Huscer,D. Tabiadon

Impact on therapeutic index of a chronomodulated infusion at conventional doses of oxaliplatin (OHP), 5-fluorouracil (5-FU) and folinic acid (AF) in not previously treated metastatic colorectal cancer patients: A multicentric observational study

2007

M. Pirovano
A. Zambelli
F. Gherardi
S. Masseroni
A. Nasisi
L. Paraboni
G. Martignoni
M Meregalli
C. S. Huscer
D. Tabiadon

14572 Background: FOLFOX4 schedule represents the standard treatment for metastatic colorectal cancer in EU, but is characterized by relevant adverse effects like G3–4 neutropenia in 42 % of patien...

Keywords:

Fluorouracil
Folinic acid
Pharmacology
Colorectal cancer
Oxaliplatin
Therapeutic index
Observational study
Medicine
Internal medicine
Adverse effect
Oncology
Neutropenia
Standard treatment

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations