Additive apoptotic effect of STI571 with the cytoprotective agent amifostine in K-562 cell line

Luciano Vellón,Marcela González-Cid,Marcelo de Campos Nebel,Irene Larripa

Additive apoptotic effect of STI571 with the cytoprotective agent amifostine in K-562 cell line

2005

Luciano Vellón
Marcela González-Cid
Marcelo de Campos Nebel
Irene Larripa

Purpose To study the apoptotic effect of the 2-phenylaminopyrimidine derivative STI571 in combination with antioxidant agents on K-562 cell line derived from a Philadelphia chromosome-positive chronic myeloid leukemia patient.

Keywords:

Amifostine
Biochemistry
Cytoprotective Agent
Superoxide dismutase
Myeloid leukemia
Pharmacology
Cell growth
Imatinib
Apoptosis
Cell culture
Medicine
Enzyme inhibitor

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