In-vivo co-registered optical coherence tomography and autofluorescence imaging in the endocervical canal and ectocervix: a pilot study (Conference Presentation)

Cervical cancer continues to be among the most frequently diagnosed and fatal cancers among women, ranking fourth in both categories globally in 2018. Detecting and treating early signs of cervical cancer drastically improves patient survivability. We will present images of the inner endocervical canal and the ectocervix taken by a fiber-based imaging system capable of co-registered Optical Coherence Tomography (OCT) and Autofluorescence Imaging (AFI). The rotary-pullback double clad fiber (DCF) imaging catheter captures 3D volumetric OCT scans and 2D AFI surface maps from within the endocervix. Images are obtained from patients undergoing colposcopy-guided biopsies or Loop Electrosurgical Excision Procedure (LEEP).