Dynamics of hormonal state in titanium and magnesium production

The authors demonstrated that work conditions for main occupations (puncher, cutter, sorter, melter) of titanium-magnesium production are characterized by combined exposure to chemical and physical environmental hazards: titanium oxide aerosol, industrial noise, local vibration, heating microclimate, work hardiness. The work conditions are assessed as hazardous (class 3.2-3.4), work process as hard (class 3.2). The female workers appeared to have reliable increased of AST and prolactine, with lower serum estradiol and FSH levels, if compared to reference group. The workers demonstrated increase in LH, SHBG, prolactine and estradiol, with decrease of free testosterone. That can result in reproductive disorders of men and women, as well as remote effects in offspring.