Quetiapine ameliorates collagen-induced arthritis in mice via the suppression of the AKT and ERK signaling pathways.

Yi-Ju Pan,Wei-Hsun Wang,Tzu-Yao Huang,Wei-Hsiang Weng,Chun-Kai Fang,Yu-Chan Chen,Jeng-Jong Hwang

Quetiapine ameliorates collagen-induced arthritis in mice via the suppression of the AKT and ERK signaling pathways.

2018

Yi-Ju Pan
Wei-Hsun Wang
Tzu-Yao Huang
Wei-Hsiang Weng
Chun-Kai Fang
Yu-Chan Chen
Jeng-Jong Hwang

Objective and design To investigate the amelioration effects of quetiapine on rheumatoid arthritis with RAW 264.7 macrophage and collagen-induced arthritis (CIA) DBA/1J mouse model.

Keywords:

Quetiapine
Biochemistry
Cancer research
Arthritis
Rheumatoid arthritis
Protein kinase B
Biology
MAPK/ERK pathway
Signal transduction
Collagen-induced arthritis
Rheumatology
Lipopolysaccharide
Pharmacology
Internal medicine
Ex vivo
Inflammation

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