Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy

Hengfeng Yuan,Wen Jiang,Christina A. von Roemeling,Yaqing Qie,Xiujie Liu,Yuanxin Chen,Yifan Wang,Robert E. Wharen,Kyuson Yun,Guojun D Bu,Keith L. Knutson,Y S Betty Kim

Multivalent bi-specific nanobioconjugate engager for targeted cancer immunotherapy

2017

Hengfeng Yuan
Wen Jiang
Christina A. von Roemeling
Yaqing Qie
Xiujie Liu
Yuanxin Chen
Yifan Wang
Robert E. Wharen
Kyuson Yun
Guojun D Bu
Keith L. Knutson
Y S Betty Kim

A multivalent bi-specific nanoconjugate can promote immune cells to recognize and eradicate cancer cells in a receptor targeted manner, leading to the generation of potent and durable anti-tumour immunity.

Keywords:

Nanotechnology
Cancer cell
Immunity
Cancer immunotherapy
Immune system
Cancer research
Physics
Receptor

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