Evaluation of phytochemical and antibacterial potential of Ajuga parviflora Benth.

Ajuga parviflora Benth. (Lamiaceae) is an annual and short-lived perennial herb grows in Himalayas’ foothills of India, Afganistan and Pakistan. In the present study hydroethanolic and hexane leaf extracts of A. parviflora were investigated for the antibacterial activities against gram negative (Escherichia coli and Pseudomonas aeruginosa) and gram positive (Bacillus subtilis and Staphylococcus aureus) bacteria. The qualitative phytochemical screening and identification of active chemical components of hydroethanolic and hexane extracts of A. parviflora using FTIR spectrum. The phytochemical analysis revealed the presence of alkaloids, flavonoids, fatty acids, phenols, steroid and terpenoids as major components in both extracts. However, the FTIR spectrums confirmed the presence of alcohols, alkanes, alkene and alkyl halides in these extracts. Antibacterial potential of extracts were evaluated by well diffusion method, showed significant sensitivity against both the tested bacteria's and the range of inhibitory zone were 8±0.23 to 20.33±0.52 mm at 25 to 200 μg/ml and the maximum zone of inhibition (ZOI) was observed in E. coli at 200 μg/ml.