Refractory arterial hypertension

: The present review synthesizes "the state of the art" concerning resistant (refractory) arterial hypertension (RAH). Definition, epidemiology, frequent risk factors, clinical conditions and causes of therapeutic resistance of RAH are revisited. Pathogenic hypothesis and related therapeutic approaches are explored. The paper lists current and new pharmacological therapies of RAH and introduces the latest interventional approach (the Rheos BHT system) to this form of arterial hypertension.