A Case of the Synchronous Multiple Esophageal Carcinoma with the Metachronous Multiple Tongue Carcinoma

Incidence of esophageal cancer among patients with head and neck cancer was estimated as about 1%. Recently, we had a rare case with double cancer of metachronous multiple tongue cancer and synchronous multiple superficial esophageal cancer.A 48 year old man admitted the hospital for his tongue ulcer. He had underwent partial resection and irradiation of tongue cancer 4 years before. Further examination revealed epidermoid carcinoma at tongue ulcer and multiple superficial esophageal cancer. The tongue cancer was estimated as metachronous multiple cancer, because the lesion occupied opposite side of the tongue to the former tumor and there suspected no continuity between them. Partial resection of the tongue and total thoracic esophagectomy were carried out. Histological studies on resected specimens disclosed the tongue cancer as T1NO (stage I) and five esophageal cancers as superficial cancer (3 mucosal cancers, and 2 submucosal cancers) . There found only one lymphnode metastasis at para-tracheal node (n=1/98) .Postoperative chemotherapy was carried out using CDDP 50 mg, MTX 30 mg and BLM 15 mg, and it repeated four times. Post operative course was uneventful.