Radioisotope-labeled and drug-loaded polymeric hydrogel and method for preparing the same, and pharmaceutical composition comprising the same for treating cancer
2011
The present invention relates to radionuclides cover and the drug-carrying polymer hydrogels and methods for their preparation, and pharmaceutical compositions for treating cancer containing the same as an active ingredient. It is possible to present the polymer hydrogel according to the invention are excellent in labeling efficiency and labeling stability of radionuclide by labeling the radionuclide to the biodegradable polymer directly and carry the hydrogel formed when the drug to minimize the free radionuclide, topically lesions is injected directly to the site can emit radiation while staying stable in the lesion be useful in the treatment of incurable diseases such as cancer. Thus, the polymer hydrogel according to the invention it is possible, as well as treatment effect due to the radionuclide expected a therapeutic effect of the drug at the same time can increase the therapeutic effects of the lesions.
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